human prostate biopsy specimens (Uman Diagnostics)
Structured Review

Human Prostate Biopsy Specimens, supplied by Uman Diagnostics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human prostate biopsy specimens/product/Uman Diagnostics
Average 90 stars, based on 1 article reviews
Images
1) Product Images from "Thrombospondin-1 Regulates the Normal Prostate In Vivo Through Angiogenesis and TGF-? Activation"
Article Title: Thrombospondin-1 Regulates the Normal Prostate In Vivo Through Angiogenesis and TGF-? Activation
Journal:
doi: 10.1038/labinvest.2010.90
Figure Legend Snippet: TSP-1 expression increases following androgen ablation in the mouse prostate and in patient-matched biopsy specimens in vivo. Prostate tissue sections were immunostained with anti-TSP antibody. (a) Prostate tissues were collected from intact or castrated (1-21 days post-castration; n=5 per group) wildtype (C57Bl/6) mice. Sections from intact and 3 days post-castration are shown. (b) TSP-1 staining intensity was graded on a 1-4 scale in the epithelium and stroma of the dorsal prostate. (c) The vessels were counted in the dorsal prostate stroma and the MVD:TSP-1 staining ratio calculated. (d) Patient-matched biopsies were taken from PCa patients before and 3-7 days after androgen ablation therapy. Six of eight patient tissues showed increased immunoreactivity following androgen ablation therapy. Pre- and post-therapy tissues are shown for two patients. (e) TSP-1 staining was graded on a 1-4 scale in the epithelial and stromal compartments. *Significantly increased in castrated compared to intact, P<0.012, and **significantly increased in human post-ADT tissues, P<00.013.
Techniques Used: Expressing, In Vivo, Staining